Not crude at all as its life. Any change to the norm with your body needs to be put to your Dr. People also need to check things with reguards to medication like if your AD's affect the pill etc. I had a cold a few weeks back and I was advised off using standard decongestant cold remedies by the pharmacist due to my dosage of amatriptyline. If you notice anything always consult, its better to know if its a normal thing or not rather than leaving it.