I've taken fluoxetine on several occasions over the past seven years. It's always worked for me. Some people do report side effects but tbh I never found that to be a problem while I was on them. The most I found was that they supressed my appetite and made me nauseous for the first couple of weeks but that subsided over time.
When the time came to come off them I've never experienced any ill effects from that either. Just a couple of weeks on reduced dosage, a couple of weeks taking one on alternate days and then off.