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Hi Noel, I take 50mg immediate-release Quetiapine at bedtime to help me sleep, in conjunction with an antidepressant. As long as I don't take the Quetiapine too late, I don't have much trouble getting up in the morning.
If 150mg is making you too drowsy to work, perhaps you could ask the GP if combining with an antidepressant would be suitable for you, or switching to the prolonged-release?
I have found that the Quetiapine has been amazing at quietening down all the 'noise' in my head, even at such a low dose.
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