I take 50mg of immediate-release quetiapine at night. From the first dose, it had the immediate effect of calming down my obsessive thoughts and allowing me to sleep deeply.
Over time my obsessive thoughts have calmed down overall and I know I can usually get a good night's sleep, without feeling groggy the next day.
I take this in conjunction with 60mg Fluoxetine.
I have found this medicine hugely beneficial.