I struggled with duloxetine for a month trying to cross taper with mirtazapine. I was sick (vomiting) every night for a month. I thought if I stuck with it the side effects would go away. They did not. I was nauseated and giddy to the point when I fell over going to the bathroom. So you were not alone with your reaction Rose. I wanted duloxetine to work but it did not. I had sexual side effects too. I felt like a freak. I was an over medicated freak!