I am on Amitriptyline for both pain and depression 75mg dose. It helps me sleep and is a good layering system to keep pain to a manageable threshold that can be assisted in pain spikes by tramadol I have been perscribed. My Amy is taken at night to help me sleep, I have forgotten doses before and it took a few nioghts of lack of sleep for it to level off which is why we always say follow the dose and remember to take it like clockwork.