Hi and welcome. You say you've decided to lower the dose, has the doctor advised this, because changing doses without medical attention is very unwise. When was the last time she saw her doctor?

I have to say that I haven't heard about this reaction you've described from taking Sertraline, but it is common with people with depression to push those closest to us away. And you've seen her at her worst, that is difficult for either of you to forget. Can I ask if she had treatment for her cuts?