Hi I'm new here. Been on anti depressants for depression and anxiety for over 20 years. I've managed finally to reduce my Duloxetine sufficiently to try augmentation with another drug. My mental health team asked me today, had I looked at different meds to augment with Duloxetine. I'm very interested to here what combinations others have tried. I've been on Duloxetine 120 mg and quetiepine 100, some affect but still very low and anxious. I'm down to 75 mg Duloxetine now and 15 mg quetiepine, so am in a very good position for my psychiatrist to try another strategy.

Lithium has been mentioned. As its a mood balancer it worries me that I won't be able to feel happy. ( not that I ever do anyway).

Mirtazipine has been mentioned.

Aripiprazole, but can't take it because of impulse control side affects, and I'm a recovering alcoholic, 18 months sober.

Any info would be gratefully appreciated